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The U.S. Senate's permanent subcommittee on investigations will probe Mylan Pharmaceuticals' pricing of the allergy auto-injector EpiPen, according to a press release issued on Wednesday.

The release described the probe as a "preliminary inquiry."

Mylan has been criticized - including by Democratic presidential candidate Hillary Clinton - for sharply raising the price of EpiPens, which are carried by people with life-threatening allergies. Mylan raised the price from about $100 in 2008 to about $600 currently. It has offered some discounts but this has done little to allay concerns.

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"Our review of this matter will be robust, thorough, and bipartisan. Parents and school districts in Ohio, Missouri and across the country need affordable access to this life-saving drug, and we share their concern over Mylan's sustained price increases," Senators Rob Portman, the Republican chair of the subcommittee, and Claire McCaskill, the top Democrat, said in a statement.

Mylan did not immediately respond to a request for comment.