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Patrick Clancy took the stand Monday and described watching his wife fall into a "big spiral" before she allegedly strangled their three young children inside the family’s Massachusetts home.

Testifying as the first witness in Lindsay Clancy’s murder trial, Patrick said his then-wife lost weight, became severely depressed and began expressing suicidal thoughts after she was prescribed Seroquel.

"Awful," Patrick said when asked how she was doing physically after beginning the medication. "That was really where her big spiral started. She started to lose a lot of weight, and she became very depressed, and she was having a really hard time."

LINDSAY CLANCY’S HUSBAND COULD TESTIFY FOR HER AT TRIAL OVER DEATHS OF THEIR THREE CHILDREN

Lindsay Clancy

Lindsay Clancy reacts as the details of her children's deaths are read in court on Monday. (Greg Derr/Pool/The Patriot Ledger)

Patrick testified that Lindsay later told him she was suicidal, although she denied having a plan to kill herself. He said she also described experiencing intrusive thoughts about harming their children.

"I never saw Lindsay harm the kids," he testified.

Patrick Clancy

Patrick Clancy took the stand around 11:45 a.m. as the first witness in the trial. Patrick and Lindsay Clancy were married at the time their three children were killed in the couple's Duxbury, Massachusetts home. They have since divorced and Patrick is remarried.  (Pool)

His testimony came after prosecutors and defense attorneys offered starkly different accounts of the deaths of Cora, 5, Dawson, 3, and Callan, 8 months, during opening statements in Plymouth Superior Court.

Prosecutor Shanan Buckingham told jurors that the children were "deliberately and meticulously killed" by their mother on Jan. 24, 2023.

"They were strangled — deliberately and meticulously killed by this defendant," Buckingham said shortly after beginning the prosecution’s opening statement.

Buckingham urged the panel of 12 women and six men to keep an open mind, use their common sense and weigh the evidence presented during the trial.

Defense attorney Kevin Reddington countered that Clancy deeply loved and cared for her children and did not kill them because she viewed them as an impediment to her life.

"These children were loved and nurtured and cared for by her," Reddington told jurors. "She didn’t want to get rid of her kids because of her selfish life. As the government indicates, she loved those children right up to the time of their death."

Clancy, a former labor and delivery nurse at Massachusetts General Hospital, has pleaded not guilty to three counts each of murder and strangulation. Her attorneys contend she was suffering from severe postpartum psychosis and was not criminally responsible for her actions.

Lindsay Clancy

Lindsay Clancy was indicted on three counts each of murder in the 2023 deaths of her 5-year-old daughter Cora, 3-year-old son Dawson and 7-month-old son Callan. She pleaded not guilty to the charges. (Greg Derr/The Patriot Ledger via Pool)

Patrick testified that he and Lindsay met in 2013 and later began dating. He said she experienced anxiety after each of their children’s births, particularly as the end of her maternity leave approached.

He recalled Lindsay telling him that she planned to begin taking Zoloft because she believed it would help with her anxiety and her return to work.

"She said, ‘I think it’s really going to help with my anxiety and with going back to work,’" Patrick testified.

When he asked how she planned to obtain the prescription, Patrick recalled her saying, "Usually you just ask the doctor, and they’ll give it to you."

Patrick also said he became concerned after Lindsay was prescribed 10 medications in slightly more than two months. He pushed for her to receive an in-person medical evaluation because many of her telehealth appointments appeared brief and lacked sufficient attention, he testified.

"I felt like it had to be in person because I just felt like there was a disconnect," Patrick said.

Plymouth County Assistant District Attorney Shanan Buckingham

Plymouth County Assistant District Attorney Shanan Buckingham delivers her opening statement in court on Monday.  (Greg Derr/Pool/The Patriot Ledger)

Her attorneys do not dispute that she killed the children but plan to argue that she was experiencing postpartum psychosis and lacked criminal responsibility. Prosecutors allege the killings were intentional and carefully planned.

"It is usually a hard battle to win," criminal defense attorney and Fox News contributor Donna Rotunno told Fox News Digital of the defense's insanity bid. "But given the fact that she has such a documented history of treatment and going to doctors and being diagnosed and seeking out more treatment when she wasn’t doing well, I think she can lay the groundwork for it."

Rotunno said Clancy’s attorneys are likely to emphasize that her condition allegedly continued to deteriorate even as she sought medical help.

"She continued to get worse. She continued to seek treatment," Rotunno said, pointing to reports that Clancy discussed hearing voices and was prescribed several medications before the children’s deaths.

Clancy’s prior work as a nurse could cut both ways at trial. Prosecutors may argue that her medical background made her more capable of understanding her treatment and actions, but Rotunno said the defense could use the same fact to demonstrate the severity of her alleged psychosis.

"She was a nurse and still so out of it that she didn’t know she shouldn’t be taking all this stuff," Rotunno said. "That, to me, doesn’t play into the intention on this. It’s the total opposite."

Lindsay Clancy

Lindsay Clancy with two of her three children in this undated photo. (Lindsay Marie Clancy/ Facebook)

Authorities said Patrick Clancy left the family’s Duxbury home on Jan. 24, 2023, to pick up takeout food and an item from a pharmacy.

While he was gone, prosecutors allege, Lindsay Clancy used exercise bands to strangle the children before jumping from a second-story window in an apparent suicide attempt.

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The fall left her paralyzed, and she now uses a wheelchair.

Cora and Dawson were pronounced dead after being taken to a Plymouth hospital. Callan was flown to Boston Children’s Hospital and died several days later. The medical examiner determined that Cora and Dawson died from asphyxia and that Callan died from complications of asphyxia.

Lindsay Clancy's blue, two story house.

Exterior view of the home of Patrick and Lindsay Clancy in Duxbury, MA on Wednesday, Feb. 15, 2023. Lindsay Clancy, 32, allegedly killed their three children here before attempting to take her own life on Jan. 24, 2023. (David McGlynn for Fox News Digital)

Clancy’s mental condition in the months and weeks before the killings are expected to become the central battleground at trial.

LUIGI MANGIONE OVERRULED HIS OWN LAWYERS WITH A 'CHANGE OF HEART' ON PSYCH DEFENSE, LEGAL EXPERT SAYS

Her attorneys say she sought help repeatedly as she struggled with depression, sleeplessness, suicidal thoughts and voices urging her to harm herself and the children.

If you or someone you know is having thoughts of suicide, please contact the National Suicide Prevention Lifeline at 1-800-273-TALK (8255).

If you or someone you know is having thoughts of suicide, please contact the National Suicide Prevention Lifeline at 1-800-273-TALK (8255).

She was admitted to a psychiatric hospital weeks before the deaths and was prescribed several medications as providers attempted to treat her worsening symptoms.

According to lawsuits filed by Lindsay and Patrick Clancy against her medical providers, she heard a voice on the day of the killings telling her it was her "last chance" to kill the children and herself.

The lawsuits accuse her providers of failing to properly diagnose, treat and monitor a severe postpartum psychiatric condition.

Lindsay Clancy

The defense is expected to argue Clancy lacks criminal responsibility because she suffered from postpartum psychosis and was overmedicated. (Greg Derr/The Patriot Ledger via Pool)

Plymouth Superior Court Judge William Sullivan ruled Friday that the media and public may not record, display, reproduce or distribute Patrick Clancy’s initial 911 call or autopsy photographs of the children.

The ruling came after Patrick requested that the evidence be shielded by media dissemination.

Reporters may also describe what is heard or shown in court but cannot broadcast or publish the recording or images themselves, according to the two-page order.

Lindsay Clancy's backyard, filled with children's toys.

Exterior view of the home of Patrick and Lindsay Clancy in Duxbury, Massachusetts, on Wednesday, Feb. 15, 2023. (David McGlynn for Fox News Digital)

The privacy dispute produced a heated courtroom exchange Thursday after the jury was seated.

Patrick Clancy asked Sullivan to limit the public and media’s ability to record, broadcast or distribute his initial 911 call, family and crime-scene photographs of the children, autopsy images and the clothing the children were wearing.

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His attorney, David Meier, said the request was not intended to close the courtroom, prevent jurors from seeing the evidence or interfere with either side’s case. Instead, he argued that allowing the materials to circulate online would cause lasting emotional harm to Patrick Clancy.

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Lindsay Clancy confers with her lawyer, Kevin Reddington

Lindsay Clancy's murder trial is expected to last six to eight weeks, and the witness list contains more than 200 names. (Greg Derr/The Patriot Ledger via Pool)

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Reddington supported Patrick’s request and accused prosecutors of planning to present the evidence in a manner designed to "inflame" the jury.

"Even though we’re in a court, let’s talk a little bit about humanity," Reddington said. "Let’s talk a little bit about how we should try this case."

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Reddington said Patrick had suffered "one of the worst tragedies that anyone could ever suffer" and was attempting to rebuild his life.

"How that guy is still not an emotional basket case is beyond me. But nevertheless, he is trying hard to move on with his life. He has, as the court is aware, divorced. He’s remarried. He has a family. He has his extended family," he said.

Lindsay and Patrick Clancy

Lindsay and Patrick Clancy with two of their three children in this undated photo. (Lindsay Marie Clancy/ Facebook)

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Reddington accused the prosecution of trying "to put a circus in front of this jury" and later called its approach "reprehensible."

"The district attorney wants to put that guy on the witness stand and show little onesies with bodily fluid of his child?" he said.

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Sullivan interrupted and reminded Reddington that the issue before the court was whether the media could record or distribute the evidence, rather than whether prosecutors could introduce it at trial.

Sprague began responding that the defense wanted to "rush past what happened to these children" and "whitewash away what happened," but Sullivan cut off the exchange.

Superior Court Judge William Sullivan

Superior Court Judge William Sullivan presides over day three of jury selection Wednesday, July 22, 2026, in the triple murder trial of Lindsay Clancy, who is accused of murdering her three young children in 2023 in their Duxbury, Massachusetts home. (Greg Derr/The Patriot Ledger via Pool)

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Reddington argued that calling one first responder after another would produce cumulative testimony intended primarily to stir jurors’ emotions.

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"The Commonwealth did not choose the number of victims. The defendant did," Sprague responded. "The Commonwealth did not choose the ages of the victims. The defendant did."