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Anti-cop rage over the police-custody death of George Floyd boiled over in Brooklyn on Friday night — with an NYPD van being set on fire in Fort Greene Park and hundreds of protesters trying to surround the 88th precinct in Clinton Hill before being rebuffed by a massive police mobilization.

In all, some 200 people were arrested Friday and early Saturday in separate, heated protests in Lower Manhattan and Brooklyn, sources told The Post.

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It was 9:30 p.m. when the empty police van was set ablaze in Fort Greene Park.

In this photo provided by Khadijah, firefighters work to contain the flames from a New York City Police Department van ablaze, Friday, May 29, 2020, in the Brooklyn borough of New York, amid a protest of the death of George Floyd in police custody on Memorial Day in Minneapolis.

In this photo provided by Khadijah, firefighters work to contain the flames from a New York City Police Department van ablaze, Friday, May 29, 2020, in the Brooklyn borough of New York, amid a protest of the death of George Floyd in police custody on Memorial Day in Minneapolis. (Khadijah via AP)

A crowd of some 3,000 protesters had converged on the Barclays Center in Prospect Heights hours earlier, with police releasing chemical mace as the demonstration grew unruly and began throwing objects at cops.

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And still earlier in the day, in Lower Manhattan, at least 30 protesters were busted, including a man who allegedly punched an NYPD sergeant in the head with brass knuckles.

Protesters rally over the death of George Floyd, a black man who was in police custody in Minneapolis Friday, May 29, 2020, in New York. Floyd died after being restrained by Minneapolis police officers on Memorial Day. 

Protesters rally over the death of George Floyd, a black man who was in police custody in Minneapolis Friday, May 29, 2020, in New York. Floyd died after being restrained by Minneapolis police officers on Memorial Day.  (AP)

The brass knuckles-wielding man allegedly walloped the sergeant as crowds massed at around 4 p.m. near Centre and Leonard streets.

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At the Barclays Center, thousands of angry protesters chanted, “They’re killing us!” and “F–k those pigs” while holding signs that read, “NYPD KKK.” At one point, the crowd roared at the sound of fireworks going off.

This story originally appeared in the New York Post. For more from the Post, click here.