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The 2020 Country Music Association (CMA) Awards were rocked by several last-minute cancellations due to coronavirus concerns Wednesday night.

 Lady A, Rascal Flatts and Florida Georga Line -- some of country music's biggest acts -- were forced to drop out of their live performances in front of a national television audience. 

Roughly an hour before the show, the Lady A announced on Twitter that they would not be in attendance as expected due to coronavirus.

"Taking a look back at last year's CMA Awards and all the fun that we have every year getting to hang out with our country music family!" they began in the post. "Sadly, one of our immediate family members has just tested positive for COVID-19 this week."

The band ensured fans that so far, none of them have tested positive, but "out of love for everyone involved," they will not be attending the awards.

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"We're bummed that we won't be able to perform with Darius Rucker and Thomas Rhett, but luckily Charles [Kelley] already taped his performance with Carly Pearce so you will still be seeing him take the stage!" they continued.

After saying that they'll be cheering on their friends from home, the band urged their fans to "stay safe out there."

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Their Twitter message was also accompanied by a photo of the trio.

Lady A, right, and Rascal Flatts were among performers to pull out of the 2020 CMA Awards due to COVID-related reasons.

Lady A, right, and Rascal Flatts were among performers to pull out of the 2020 CMA Awards due to COVID-related reasons. (Getty)

Hillary Scott was also set to perform "Be a Light" with Thomas Rhett, Reba McEntire, Chris Tomlin and Keith Urban.

Just a short time after Lady A's announcement, a shocking blow was delivered to the awards show when Rascal Flatts announced during the middle of the program that they too, were out after one of their members tested positive for the novel illness.

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"Hey Y’all, we wanted to let you guys know that we have received a positive COVID test within the band," they shared on Twitter. "As much as we were looking forward to performing at the CMA Awards tonight, we will no longer be attending in the interest of everyone’s safety. We miss y’all and stay safe!"

What's more is last year's CMA musician of the year, Jenee Fleenor, was set to perform with Jason Aldean, Dierks Bentley, Brothers Osbourne and Ashley McBryde during the opening tribute to Charlie Daniels until she also relayed to her fans that she had tested positive for "yeah you guessed it...'Rona."

"Unfortunately I tested positive..., Fleenor, 36, wrote on Instagram. "I am thankfully feeling just fine, just bummed of course."

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"I'm absolutely honored the CMAs asked me to perform on the Charlie Daniels tribute, and I was so looking forward to putting on some sparkly clothes ... and sawin' my heart out," added the fiddler. "I reckon it's just another bump in the road of 2020 and as the saying goes, 'the show must go on.'

Florida Georgia Line too was set to perform until Tyler Hubbard tested positive for the novel virus.

Like Hubbard, country singer Lee Brice also tested positive for COVID-19 and will not able to perform at the CMAs with Carly Pearce.