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David Letterman is sharing his experience of recently becoming an empty nester.

Letterman, 75, was a guest on Tuesday night’s "Jimmy Kimmel Live," during which he cracked a joke about his son Harry, 18, moving away to college.

"Harry is my son, and all reports indicate that he's OK," he joked to Kimmel. "They tell me he's in college."

The former "Late Show" host noted that the transition of having Harry out of his home has not been easy.

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"I thought it would be nothing, but it's devastating," he shared. "Am I the only one that feels that way?"

The Netflix star then returned to his comical nature and recalled taking his son and his "truckload of crap" to college and carrying a sofa up three flights of stairs.

David Letterman smiling

David Letterman said his son's move to college has been "devastating." (Andrew Toth/FilmMagic)

"Is that true?" Kimmel said to Letterman.

"Is that true?" Letterman replied to Kimmel while laughing. "This stuff's gotta be true?"

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Letterman added that he’s been in touch with Harry since he moved out last month. 

"We text now and then, and I got a text from him today. … Forgive me if I'm sounding a little over-emotional about this," he said before adding Harry told him he had no classes that day.

"I'm thinking, I'm getting my money's worth here." 

David Letterman and son Harry

Harry is David Letterman and Regina Lasko's only son. (Andrew Caballero-Reynolds/AFP)

Later on in the interview, Letterman shared another conversation he’s had with his son since he moved away. 

"I called him, a week into it. 'Hi, Harry. Harry, have you met the kid yet who sells weed?'" he said. "And Harry says, 'I cannot confirm or deny.'"

The television personality and his son have shared a close bond over the years. In 2019, Letterman shared on "Sunday Today" that he has tried to be his son’s best friend.

"Look at me — how much longer am I going to be around?" Letterman asked. "I want to be the best friend."

David Letterman, Regina Lasko

Regina Lasko and David Letterman wed in 2009. (Sylvain Gaboury/Patrick McMullan)

He noted that he feels better when he is surrounded by family. "The most secure I ever feel is when I'm around my son," Letterman said. 

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Letterman shares Harry with wife Regina Lasko, 61. The couple married in 2009. He was previously married to Michelle Cook in 1968, divorcing ten years later.