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Patrick Dempsey would definitely work with Ellen Pompeo again.

The two previously starred together in "Grey's Anatomy."

"I would love to work with her again," Dempsey said during an interview with Extra.

Dempsey has a "couple ideas" for projects he'd like to do with Pompeo.

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Ellen Pompeo and Patrick Dempsey pose for a photo

Patrick Dempsey says he wants to work with Ellen Pomepo again. (Donato Sardella/WireImage via Getty Images)

"I'll tell her first and then see if we can realize them," Dempsey said. 

Dempsey noted that the "chemistry" he has with the actress is what makes him want to work together again. "Grey's Anatomy" is the longest-running primetime medical drama as well as ABC's longest-running show. The show has aired 18 seasons and has been renewed for a 19th.

"It has always been a really special relationship Ellen and I have had together in front of the screen and behind it as well," Dempsey further explained.

Ellen Pompeo and Patrick Dempsey in Grey's Anatomy

Patrick Dempsey and Ellen Pompeo as Dr. Derek Shepherd and Dr. Meredith Grey on "Grey's Anatomy." (Ron Tom ABC via Getty Images)

"I think a lot of the success of the show was because of the chemistry and the relationship, and people want to believe in love and all of that," he added. "I meet people around the world who were wishing we were actually together, but she's got Christopher [Ivery] and I have [my wife] Jillian, and they are incredible people."

While "Grey's Anatomy" won't be coming to a close any time soon, Pompeo admitted during an interview with Insider she has been working behind the scenes to halt the long-running show.

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"I've been trying to focus on convincing everybody that it should end," Pompeo told the outlet.

"​I feel like I'm the super naive one who keeps saying, 'But what's the story going to be? What story are we going to tell?' And everyone's like, 'Who cares, Ellen? It makes a gazillion dollars.'"

Ellen Pompeo on "Grey's Anatomy"

Pompeo has said she wants "Grey's Anatomy" to end. (Getty Images )

The series has made Pompeo the highest-paid drama TV star. In 2017, Pompeo cut a deal with ABC that had her earning roughly $20 million a year, according to The Hollywood Reporter.