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As thousands of Pro-Palestinian protesters gathered in Times Square earlier in the day for "Palestinian Land Day," they took their protest to the Easter Vigil service at St. Patrick's cathedral in New York City on Saturday evening.

During the second reading, chants of "Free, free Palestine" could be heard ringing out during the service. 

The protesters were quickly taken out of the service moments after, as many in attendance did not acknowledge the outburst. 

The mass was led by Cardinal Timothy Dolan, archbishop of New York.

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Exterior shot showing st. patrick's cathedral in NYC

St. Patrick's Cathedral in New York City (Roy Rochlin/Getty Images)

All over the world, millions gathered Saturday to protest the Israel-Hamas war in Gaza.

The United States Conference of Catholic Bishops (USCCB) issued a call for prayer for peace in the Middle East and an end to the Israel-Hamas war in a statement before the start of Holy Week. 

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Cardinal Dolan

Cardinal Timothy Dolan, the archbishop of New York. (Spencer Platt/Getty Images)

"As the Church enters Holy Week and Christ’s suffering on the cross and his resurrection are made present to us so vividly, we are connected to the very source of hope," the statement said.

Since the start of the war in Israel, the USCCB has consistently issued calls for peace, prayer, fasting and the release of hostages captured by Hamas. The conference has also decried the deaths of civilians. 

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"Thousands of innocent people have died in this conflict, and thousands more have been displaced and face tremendous suffering," the bishops said. "This must stop." 

Fox News Digital's Christine Rousselle and Pilar Arias contributed to this report.